

Thirty minutes after takeoff their balloon caught fire, killing both of them.

Regrettably, the first fatalities in aviation occurred on Jwhen Pierre de Rozier and Pierre Romain unsuccessfully attempted to pilot a balloon across the English Channel. Jeffries noted that his pulse increased from 84 beats per minute (bpm) at sea level, to 92 bpm at an altitude of 5812′ MSL. John Jeffries to take his pulse during a flight. Even one of the United States’ founding fathers, Benjamin Franklin, took an early interest in high altitude research when he asked early balloonist Dr. While piloting a balloon, his passenger unexpectedly exited the basket, thus lightening the balloon and triggering a rapid ascent to an approximate altitude of 10,000′ MSL, causing Charles to experience ear and sinus pain. Unfortunately, shortly thereafter in 1783, researcher Jacques Charles, of Charles’ Law fame, endured the first aviation mishap. On September 19, 1783, brothers Joseph and Etienne Montgolfier sent aloft a duck, a rooster, and a sheep to elucidate hypoxia-like effects on mammals. Research on the physiologic responses specific to flight took place among early balloonists. Later, Robert Boyle of “Boyle’s Law” fame, described the first case of decompression sickness when he observed bubble formation in the eyes of a viper exposed to vacuum environments. In honor of his accomplishments physical units of pressure were named after him and are known as torrs. Decades later, in 1643, Evangelista Torricelli created the first experimental vacuum. Evaluating the Andes high-altitude mountainous environment, Father Acosta surmised the thin “element of air” was causing animals and humans to become ill. Scientific interest in the effects of human and animal exposure to high-altitude environments can be traced to the observations of Father Jose de Acosta in the late 1590s, more than 300 years before the Wright brothers first flew their Flyer among the dunes at Kitty Hawk, North Carolina. This chapter will address emerging challenges to human health in modern “next generation” fighters as well as ways in which engineers and aerospace medicine professionals may address them. Unfortunately in recent times, there appears to be a decrease in the medical role during initial design and testing, leaving medical specialists scrambling to make sense of new physiologic ailments after an aircraft has become operational.

As human factors specialists, Aerospace Medicine specialists are ideally suited to participate in the development of new life-support systems in modern aircraft. Additionally, some specialize in human dynamics focusing on highly integrated “man-machine” challenges such as high-performance aircraft and ejection seat emergency escape technologies. Aerospace medicine practitioners often further specialize in niche aspects of aerospace medicine, applying human performance enhancement (HPE) and human systems integration (HSI) tenets to both hyperbaric environments (dive medicine) and hypobaric disciplines (space medicine, high-altitude wilderness medicine). Unique hazards in these environments include exposure to microgravity conditions, various radiation sources, multi-axial G-forces, and hypoxic conditions, among others. Aerospace Medicine is a sub-specialty within the broader Occupational Medicine discipline, requiring licensed physicians to complete specialized training to ensure and enhance the health, safety, and performance of individuals exposed to air and space operational settings.
